what supplement to take for migraine dolovent

Magnesium, Vitamin B2 and CoQ10 for Migraine

The three nutrients most studied in migraine, at the doses used in the research.

Dolovent contains 600 mg magnesium and 400 mg riboflavin at doses that contribute to a reduction in tiredness and fatigue and to the normal functioning of the nervous system. Dolovent also contains 150mg CoEnzyme Q10.

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Why Dolovent

  • 130 Patient Randomised Controlled Trial.

    In a double-blind, placebo-controlled, multicentre trial of 130 adults, the Dolovent formulation significantly reduced migraine pain intensity (p=0.03), HIT-6 disease burden (down 4.8 points vs 2 on placebo, p=0.01), and patient-rated efficacy (p=0.01). Migraine days fell from 6.2 to 4.4 per month, compared with 6.2 to 5.2 on placebo. Published in The Journal of Headache and Pain.

  • Delivers to your brain what diet alone can't.

    To get the same amount of nutrients as a Dolovent dosage from your daily food, you would need to eat:

    600mg Magnesium = 10 Heads of broccoli

    400mg Riboflavin (B2) = 14.3 kg of beef liver

    150mg CoQ10 = 1.5 kg of chicken liver

  • Dolovent Delivers in 1 Dose.

    Each dose delivers a blend of 19 different nutrients, vitamins, and minerals that support the absorption and activation of the 3 key ingredients, magnesium, riboflavin, and Coenzyme Q10, while also helping restore some of the body's natural nutrients we use daily.

How Dolovent Works Daily.

  • Month 1

    Your Daily Dolovent journey begins. The nutrients activate and replenish the minerals that you are missing. You may begin to feel more alert and energised.

  • Month 2

    The constant feeling of 'fogginess' is beginning to lift. Nutrients are being restored, and you may feel sharper.

  • Month 3

    You are feeling the full benefits of Dolovent. Your brain feels alert and energised no matter what time of day.

  • Daily Support.

    Take Dolovent Daily. Dolovent is a brain supplement that replenishes the vital nutrients and vitamins our bodies use daily. Dolovent can be used long-term.
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The Science 🔬

Dolovent contains three key ingredients blended with specific vitamins, minerals, and bioflavonoids to help increase their absorption and effectiveness. Dolovent also contains bioflavonoids, a proven nootropic ingredient.

Dolovent combines magnesium, riboflavin and CoQ10 at the doses used in migraine research, with supporting vitamins, minerals and bioflavonoids. The formulation was tested in a randomised controlled trial with 130 patients.¹

Each daily Dolovent dosage delivers:

  • Magnesium (600mg)
  • Riboflavin (400mg)
  • CoQ10 (150mg).

The three key ingredients are blended with other vitamins, minerals and bioflavonoids, which increase brain energy, reduce tiredness and fatigue, and improve neurological and psychological function. Dolovent has been researched through a 130-patient independent study to prove its effectiveness in reducing aura sufferers' feel.

Gaul et al., J Headache and Pain 2014¹.

Read Dolovent StudyWatch Interview With Migraine Specialist

Magnesium 600mg

Taking 600 mg of magnesium citrate for 12 weeks reduced attack frequency by 41.6% compared to 15.7% on placebo. Magnesium is involved in hundreds of biochemical reactions in the body, with low levels being linked to:

- Fatigue
- Muscle spasms
- Poor sleep

In peer-reviewed research, using Dolovent for three months to build nutrient levels up showed a reduction in migraine days from 6.6 to 4.2 days.

Scientific References: Peikert et al., Cephalalgia, 1996²; and Gaul et al., J Headache and Pain, 2014¹.

Read Magnesium study

Riboflavin (Vitamin b2) 400mg

Taking 400 mg of riboflavin (vitamin B2) for 12 weeks showed 59% of the riboflavin group improved by at least 50% on headache days, compared with 15% on

Riboflavin plays an important role in cellular energy production. Its role in mitochondrial energy metabolism suggests it may help.

Although normal levels of magnesium, B2, and CoQ10 may be restored in as little as a week, clinical evidence shows Dolovent is most effective when taken regularly.

Schoenen et al., Neurology, 1998³

Read Riboflavin Study

CoEnzyme Q10 (CoQ10) 150mg

In a study of 32 adults with episodic migraine taking 150mg CoQ10, 61.3% had a greater than 50% reduction in migraine days; mean days fell from 7.34 to 2.95.

Co-enzyme Q10 plays an important role in brain energy. CoQ10 supports brain processes and provides the fuel our brain needs to function.

Research shows that decreased levels of CoQ10 are linked to physical fatigue and muscle weakness, even when doing simple tasks. Our CoQ10 levels decrease as we get older (25+).

Rozen et al., Cephalalgia, 2002⁴

Read CoQ10 Study

Migraine Supplements Aren't Created Equally.

3 in 1 Complete Formulation. Backed by a 130-patient RCT.

Most brain supplements contain a blend of B vitamins or single nutrients. They have limited or no research, so you end up taking multiple products, capsules and tablets, hoping to feel a benefit.

Dolovent delivers all the key nutrients and vitamins in 1 dose. No gimmicks, no might-dos or maybe's. 3 research-backed ingredients blended with nutrients that restore key nutrients for brain health. All backed and supported by our 130-patient RCT.

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Dolovent migraine supplement for headaches

Environmental Impact.

Many 'cheap' supplements are produced using low-paid labour and low-quality materials, then shipped abroad. We don't. We make all our products in the UK at our GMP-certified facility.

You won't find plastic bottles here. We don't contribute to landfill or release microplastics. Nope, Dolovent is packed in 100% recyclable pouches. Even our packing peanuts are made from food-grade starch. Run them under a tap, and watch them disappear!

Written by the Made By Daily team. Medically reviewed by Tracey Raye, registered nutritional therapist.

Last reviewed: 15 September 2026.

We update this page when new trial evidence is published.

Disclaimer: This article is for informational purposes only and does not constitute medical advice. Please consult a qualified healthcare practitioner before changing your diet, supplement regimen, or medical treatment.

References

Studies are listed in the order they appear on this page. Links go to the publisher of record.

  1. Gaul C, Diener HC, Danesch U; Migravent Study Group. Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial. J Headache Pain. 2015;16:516. doi:10.1186/s10194-015-0516-6
  2. Peikert A, Wilimzig C, Köhne-Volland R. Prophylaxis of migraine with oral magnesium: results from a prospective, multi-center, placebo-controlled and double-blind randomized study. Cephalalgia. 1996;16(4):257-63. doi:10.1046/j.1468-2982.1996.1604257.x
  3. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis: a randomized controlled trial. Neurology. 1998;50(2):466-70. doi:10.1212/WNL.50.2.466
  4. Rozen TD, Oshinsky ML, Gebeline CA, Bradley KC, Young WB, Shechter AL, et al. Open-label trial of coenzyme Q10 as a migraine preventive. Cephalalgia. 2002;22(2):137-41. doi:10.1046/j.1468-2982.2002.00335.x